T¡¡F¡¡9¡£¡¡Those¡¡people¡¡who¡¡never¡¡mention¡¡suicide¡¡are¡¡more¡¡likely¡¡to¡¡
actually¡¡mit¡¡the¡¡act¡¡than¡¡individuals¡¡who¡¡occasionally¡¡
discuss¡¡it¡£¡¡
T¡¡F¡¡10¡£¡¡One¡¡of¡¡the¡¡difficulties¡¡in¡¡predicting¡¡suicides¡¡is¡¡that¡¡they¡¡are¡¡
often¡¡mitted¡¡without¡¡warning¡£¡¡
425¡¡
EVALUATION¡¡AND¡¡RESEARCH¡¡ETHICS¡¡
OBJECTIVES¡¡
1¡£¡¡To¡¡acquaint¡¡students¡¡with¡¡the¡¡ethical¡¡issues¡¡surrounding¡¡research¡¡with¡¡human¡¡subjects¡£¡¡
2¡£¡¡To¡¡consider¡¡the¡¡perspective¡¡of¡¡prospective¡¡investigators¡¡and¡¡the¡¡institutional¡¡review¡¡boards¡¡that¡¡are¡¡
designed¡¡to¡¡minimize¡¡or¡¡prevent¡¡harmful¡¡research¡¡procedures¡£¡¡
3¡£¡¡To¡¡create¡¡a¡¡role¡playing¡¡situation¡¡that¡¡vividly¡¡illustrates¡¡the¡¡review¡¡process¡¡for¡¡use¡¡of¡¡subjects¡¡in¡¡
research¡£¡¡
OVERVIEW¡¡
The¡¡same¡¡research¡¡procedures¡¡that¡¡can¡¡lead¡¡to¡¡helpful¡¡gains¡¡in¡¡knowledge¡¡may¡¡also¡¡represent¡¡a¡¡source¡¡of¡¡
danger¡¡to¡¡the¡¡individuals¡¡who¡¡serve¡¡as¡¡subjects¡£¡¡The¡¡power¡¡of¡¡the¡¡researcher¡¡and¡¡of¡¡the¡¡scientific¡¡
establishment¡¡relative¡¡to¡¡that¡¡of¡¡their¡¡subjects¡¡has¡¡been¡¡balanced¡¡in¡¡recent¡¡years¡¡by¡¡the¡¡creation¡¡of¡¡
institutional¡¡review¡¡boards¡¡£¨IRBs£©¡£¡¡These¡¡peer¡¡review¡¡mittees¡¡have¡¡established¡¡evaluation¡¡procedures¡¡
that¡¡protect¡¡the¡¡welfare¡¡of¡¡human¡¡and¡¡animal¡¡subjects¡£¡¡How¡¡does¡¡evaluation¡¡of¡¡the¡¡ethics¡¡of¡¡research¡¡
operate£¿¡¡What¡¡is¡¡the¡¡process¡¡by¡¡which¡¡an¡¡individual¡¡investigator¡¡submits¡¡a¡¡research¡¡proposal¡¡to¡¡a¡¡
university¡¡IRB¡¡for¡¡its¡¡evaluation£¿¡¡In¡¡this¡¡section¡¡we¡¡will£º¡¡
1¡£¡¡Begin¡¡by¡¡discussing¡¡instances¡¡of¡¡research¡¡with¡¡unacceptable¡¡risks¡¡and¡¡questionable¡¡ethics¡¡£¨see¡¡
Additional¡¡Resources£©¡£¡¡
2¡£¡¡Discuss¡¡the¡¡essential¡¡concepts¡¡of¡¡¡°at¡¡risk£»¡±¡¡¡°invasion¡¡of¡¡privacy£»¡±¡¡¡°deception£»¡±¡¡¡°informed¡¡consent£»¡±¡¡
¡°the¡¡gain/loss¡¡notion¡¡of¡¡relative¡¡ethics£»¡±¡¡and¡¡the¡¡raising¡¡of¡¡consciousness¡¡about¡¡ethical¡¡
considerations¡£¡¡
3¡£¡¡Briefly¡¡describe¡¡the¡¡review¡evaluation¡¡procedure¡¡now¡¡required¡¡of¡¡prospective¡¡researchers¡¡in¡¡an¡¡
academic¡¡setting¡£¡¡
4¡£¡¡Briefly¡¡describe¡¡the¡¡importance¡¡to¡¡society¡¡of¡¡promoting¡¡scientific¡¡progress¡¡and¡¡the¡¡career¡¡of¡¡the¡¡
individual¡¡researcher¡¡£¨in¡¡order¡¡to¡¡establish¡¡social¡¡and¡¡personal¡¡values¡¡that¡¡oppose¡¡¡°undesirable¡±¡¡
constraints£©¡£¡¡
5¡£¡¡Conduct¡¡the¡¡demonstrations¡¡on¡¡role¡playing¡¡in¡¡which¡¡students¡¡take¡¡both¡¡sides¡¡in¡¡the¡¡institutional¡¡
evaluation¡¡of¡¡psychological¡¡research¡¡proposed¡¡by¡¡independent¡¡investigators¡£¡¡
GENERAL¡¡INTRODUCTION¡¡
Ethical¡¡questions¡¡often¡¡arise¡¡about¡¡the¡¡conduct¡¡of¡¡scientific¡¡research¡¡because¡¡it¡¡may¡¡intervene¡¡in¡¡the¡¡lives¡¡of¡¡
participants¡¡who¡¡are¡¡subject¡¡to¡¡its¡¡procedures¡even¡¡if¡¡only¡¡for¡¡a¡¡short¡¡time¡£¡¡Decisions¡¡made¡¡by¡¡investigators¡¡
solely¡¡based¡¡on¡¡scientific¡¡or¡¡pragmatic¡¡considerations¡¡may¡¡be¡¡harmful¡¡to¡¡research¡¡subjects¡£¡¡The¡¡subjects¡¡are¡¡
usually¡¡not¡¡in¡¡a¡¡position¡¡to¡¡have¡¡advance¡¡knowledge¡¡of¡¡what¡¡will¡¡be¡¡done¡¡to¡¡them¡¡or¡¡to¡¡refuse¡¡exposure¡¡to¡¡
procedures¡¡unacceptable¡¡to¡¡them¡£¡¡Much¡¡research¡¡takes¡¡place¡¡in¡¡institutional¡¡settings¡¡where¡¡there¡¡are¡¡strong¡¡
pressures¡¡on¡¡potential¡¡subjects¡¡to¡¡ply¡¡with¡¡authorities£»¡¡such¡¡as¡¡in¡¡prisons£»¡¡the¡¡military£»¡¡factories£»¡¡
summer¡¡camps£»¡¡schools£»¡¡and¡¡colleges¡£¡¡
Research¡¡involving¡¡human¡¡subjects¡¡raises¡¡ethical¡¡and¡¡legal¡¡issues¡¡of¡¡sufficiently¡¡serious¡¡and¡¡widespread¡¡
concern¡¡that¡¡a¡¡prehensive¡¡mechanism¡¡has¡¡been¡¡developed¡¡through¡¡which¡¡the¡¡judgments¡¡of¡¡researchers¡¡
are¡¡reviewed¡£¡¡Under¡¡the¡¡National¡¡Research¡¡Act¡¡of¡¡1974£»¡¡institutions¡¡applying¡¡for¡¡funds¡¡must¡¡establish¡¡an¡¡
IRB¡¡to¡¡review¡¡research¡¡conducted¡¡by¡¡that¡¡institution¡£¡¡Of¡¡course£»¡¡many¡¡institutions¡¡and¡¡departments¡¡already¡¡
had¡¡established¡¡IRBs¡¡prior¡¡to¡¡this¡¡act£»¡¡including¡¡most¡¡psychology¡¡departments£»¡¡which¡¡supported¡¡¡°Human¡¡
Subject¡¡mittees£»¡±¡¡to¡¡review¡¡psychological¡¡research¡£¡¡The¡¡IRB¡¯s¡¡goals£»¡¡then£»¡¡are¡¡to¡¡determine¡¡whether¡¡
subjects¡¡will¡¡be¡¡placed¡¡at¡¡risk£»¡¡and£»¡¡if¡¡so£»¡¡whether¡¡the¡¡risks¡¡are¡¡outweighed¡¡by¡¡the¡¡benefits¡¡to¡¡the¡¡subject¡¡and¡¡
the¡¡importance¡¡of¡¡the¡¡knowledge¡¡being¡¡sought¡£¡¡In¡¡addition£»¡¡it¡¡is¡¡necessary¡¡to¡¡determine¡¡if¡¡the¡¡rights¡¡and¡¡
426¡¡
welfare¡¡of¡¡the¡¡subjects¡¡are¡¡protected¡¡and¡¡if¡¡¡°legally¡¡effective¡¡informed¡¡consent¡±¡¡will¡¡be¡¡obtained¡¡by¡¡adequate¡¡
and¡¡appropriate¡¡means¡£¡¡
The¡¡purpose¡¡of¡¡the¡¡evaluation¡¡procedure¡¡is¡¡to¡¡protect¡¡the¡¡welfare¡¡of¡¡human¡¡subjects¡£¡¡This¡¡includes¡¡
protection¡¡against¡¡undue¡¡or¡¡unnecessary¡¡invasion¡¡of¡¡privacy£»¡¡disrespect¡¡for¡¡human¡¡dignity£»¡¡and¡¡physical£»¡¡
physiological£»¡¡or¡¡social¡¡harm¡£¡¡
In¡¡this¡¡demonstration¡¡we¡¡want¡¡students¡¡to¡¡discuss¡¡research¡¡ethics¡¡by¡¡having¡¡them¡¡participate¡¡in¡¡several¡¡
role¡playing¡¡scenarios¡¡in¡¡which¡¡experimenters¡¡defend¡¡their¡¡proposals¡¡before¡¡an¡¡IRB¡£¡¡To¡¡give¡¡them¡¡good¡¡
material¡¡to¡¡work¡¡with£»¡¡we¡¡have¡¡prepared¡¡proposals¡¡modified¡¡from¡¡several¡¡experiments¡¡that¡¡have¡¡proven¡¡
over¡¡the¡¡years¡¡to¡¡generate¡¡a¡¡fair¡¡amount¡¡of¡¡controversy¡£¡¡
PROCEDURE¡¡
Materials¡¡
Four¡¡research¡¡proposal¡¡summaries¡¡of¡¡relevant¡¡parts¡¡of¡¡psychological¡¡experiments¡£¡¡Each¡¡of¡¡them¡¡includes¡¡
procedures¡¡that¡¡raise¡¡questions¡¡about¡¡its¡¡ethics¡£¡¡The¡¡proposals¡¡are¡¡based¡¡on¡¡research¡¡by£º¡¡
1¡£¡¡Sherif¡¡and¡¡associates¡¡on¡¡intergroup¡¡conflict¡¡among¡¡children¡¡in¡¡a¡¡summer¡¡camp¡¡£¨not¡¡usually¡¡
described¡¡in¡¡the¡¡literature¡¡as¡¡ethically¡¡questionable£©¡£¡¡
2¡£¡¡Freedman¡¡and¡¡Fraser¡¯s¡¡foot¡in¡the¡door¡¡pliance¡¡field¡¡experiment¡£¡¡
3¡£¡¡Sheridan¡¡and¡¡King¡¯s¡¡modification¡¡of¡¡Milgram¡¯s¡¡obedience¡¡study¡¡
4¡£¡¡Zimbardo¡¯s¡¡prison¡¡simulation¡£¡¡
Subjects¡¡
15¡25¡¡students¡¡are¡¡ideal¡£¡¡Four¡¡are¡¡selected¡¡to¡¡act¡¡as¡¡university¡¡research¡¡professors£»¡¡each¡¡advocating¡¡
approval¡¡of¡¡his¡¡or¡¡her¡¡proposal¡£¡¡The¡¡rest¡¡of¡¡the¡¡class¡¡serves¡¡as¡¡the¡¡IRB¡¡£¨see¡¡variations¡¡for¡¡a¡¡possible¡¡third¡¡role¡¡
for¡¡2¡¡impression¡¡management¡¡observers£©¡£¡¡
Time¡¡Required¡¡for¡¡Role¡Playing¡¡
20¡45¡¡minutes¡¡for¡¡the¡¡presentation£»¡¡questioning¡¡and¡¡evaluation¡¡of¡¡the¡¡four¡¡proposals¡¡£¨5¡15¡¡minutes¡¡for¡¡each¡¡
depending¡¡on¡¡the¡¡intensity¡¡and¡¡detail¡¡of¡¡the¡¡role¡playing£©¡£¡¡
Time¡¡Required¡¡for¡¡Discussion¡¡
10¡20¡¡minutes¡£¡¡
Method¡¡
1¡£¡¡Decide¡¡which¡¡of¡¡the¡¡research¡¡proposals¡¡will¡¡be¡¡presented¡¡to¡¡the¡¡class¡¡IRB£»¡¡depending¡¡on¡¡your¡¡time¡¡
schedule¡£¡¡You¡¡may¡¡want¡¡to¡¡add¡¡one¡¡or¡¡more¡¡of¡¡your¡¡own¡¡choosing¡¡or¡¡use¡¡only¡¡a¡¡few¡¡of¡¡ours¡£¡¡
2¡£¡¡Preselect¡¡the¡¡research¡¡investigators¡¡who¡¡will¡¡argue¡¡for¡¡their¡¡proposals£»¡¡either¡¡assigning¡¡them¡¡the¡¡
previous¡¡week¡¡to¡¡bee¡¡familiarized¡¡with¡¡the¡¡specific¡¡proposals¡¡or¡¡choosing¡¡students¡¡who¡¡arrive¡¡
early¡¡to¡¡the¡¡section¡£¡¡In¡¡a¡¡large¡¡class£»¡¡you¡¡may¡¡want¡¡to¡¡have¡¡pairs¡¡of¡¡students¡¡be¡¡a¡¡research¡¡team¡£¡¡
3¡£¡¡Explain¡¡the¡¡role¡playing¡¡scenario¡£¡¡The¡¡researchers£»¡¡eager¡¡to¡¡begin¡¡their¡¡research¡¡as¡¡soon¡¡as¡¡possible¡¡
with¡¡minimal¡¡modifications£»¡¡have¡¡submitted¡¡a¡¡proposal¡¡for¡¡the¡¡experiment¡¡to¡¡the¡¡human¡¡subjects¡¡
mittee¡¡for¡¡review¡£¡¡They¡¡have¡¡received¡¡a¡¡reply¡¡from¡¡the¡¡mittee¡¡stating¡¡that¡¡there¡¡are¡¡some¡¡
ethical¡¡£¨and¡¡possibly¡¡other£©¡¡questions¡¡about¡¡the¡¡study£»¡¡and¡¡that¡¡they¡¡have¡¡been¡¡requested¡¡to¡¡appear¡¡
before¡¡the¡¡mittee¡¡to¡¡defend¡¡their¡¡proposal¡¡and¡¡presentation¡¡strategy¡£¡¡They¡¡should¡¡attempt¡¡to¡¡
defend¡¡it¡¡as¡¡best¡¡they¡¡can£»¡¡given¡¡the¡¡material¡£¡¡You¡¡might¡¡even¡¡inform¡¡them¡¡that¡¡their¡¡entire¡¡career¡¡
and¡¡everything¡¡they¡¯ve¡¡worked¡¡for¡¡depends¡¡on¡¡getting¡¡this¡¡study¡¡through¡¡the¡¡mittee¡¡£¨with¡¡
reasonable¡¡modifications£©¡£¡¡
4¡£¡¡The¡¡IRB¡¡should¡¡read¡¡the¡¡study£»¡¡each¡¡member¡¡listing¡¡questions¡¡to¡¡raise¡£¡¡You¡¡may¡¡want¡¡to¡¡alert¡¡them¡¡
to¡¡some¡¡specific¡¡concerns¡¡they¡¡might¡¡miss¡£¡¡Appoint¡¡a¡¡chairperson¡¡to¡¡coordinate¡¡the¡¡session¡£¡¡With¡¡a¡¡
large¡¡class¡¡you¡¡might¡¡save¡¡time¡¡with¡¡two¡¡IRBs£»¡¡the¡¡second¡¡one¡¡preparing¡¡the¡¡materials¡¡for¡¡Proposals¡¡
427¡¡
2¡¡and¡¡4¡¡while¡¡the¡¡first¡¡does¡¡1¡¡and¡¡3¡£¡¡
5¡£¡¡The¡¡first¡¡experimenters¡¡are¡¡invited¡¡to¡¡present¡¡the¡¡reasons¡¡for¡¡seeking¡¡approval¡¡of¡¡their¡¡research¡£¡¡
Then¡¡the¡¡mittee¡¡members¡¡raise¡¡their¡¡concerns¡¡and¡¡objections¡£¡¡The¡¡experimenters¡¡have¡¡a¡¡chance¡¡
to¡¡reply£»¡¡after¡¡which¡¡a¡¡group¡¡IRB¡¡decision¡¡is¡¡made¡£¡¡
6¡£¡¡Follow¡¡the¡¡same¡¡procedure¡¡for¡¡each¡¡additional¡¡proposal¡£¡¡
7¡£¡¡Throughout¡¡the¡¡section£»¡¡you¡¡may¡¡act¡¡as¡¡moderator¡¡£¨or¡¡devil¡¯s¡¡advocate£©¡¡to¡¡lend¡¡support¡¡to¡¡one¡¡side¡¡
or¡¡the¡¡other¡¡if¡¡the¡¡discussion¡¡gets¡¡bogged¡¡down¡¡or¡¡is¡¡missing¡¡important¡¡points¡£¡¡
PITFALLS¡¡TO¡¡AVOID¡¡
1¡£¡¡Be¡¡sure¡¡to¡¡create¡¡a¡¡present¡time¡¡perspective¡¡of¡¡this¡¡event¡¡unfolding¡¡now¡¡in¡¡order¡¡to¡¡maximize¡¡
personal¡¡involvement¡£¡¡
2¡£¡¡Set¡¡time¡¡limits¡¡for¡¡review¡¡of¡¡each¡¡proposal£»¡¡if¡¡heated¡¡discussion¡¡arises£»¡¡it¡¡is¡¡easy¡¡to¡¡run¡¡overtime¡£¡¡
3¡£¡¡Establish¡¡the¡¡important¡¡role¡¡of¡¡the¡¡IRB¡¡and¡¡possible¡¡student¡¡representation¡¡on¡¡it£»¡¡in¡¡order¡¡for¡¡the¡¡
class¡¡members¡¡to¡¡take¡¡their¡¡roles¡¡seriously¡£¡¡
DATA¡¡ANALYSIS¡¡AND¡¡INTERPRETATION¡¡
1¡£¡¡What¡¡is¡¡the¡¡overall¡¡verdict¡¡of¡¡the¡¡mittee¡¡on¡¡the¡¡studies¡¡in¡¡question£¿¡¡What¡¡are¡¡the¡¡individual¡¡
verdicts£¿¡¡Are¡¡there¡¡any¡¡studies¡¡that¡¡split¡¡the¡¡mittee¡¡or¡¡caused¡¡a¡¡stalemate£¿¡¡
2¡£¡¡Analyze¡¡and¡¡summarize¡¡specific¡¡features¡¡of¡¡proposals¡¡that¡¡were¡¡found¡¡objectionable¡£¡¡
3¡£¡¡Review¡¡specific¡¡arguments¡¡that¡¡were¡¡effective¡¡or¡¡ineffective¡¡in¡¡persuading¡¡the¡¡IRB¡¡to¡¡approve¡¡the¡¡
research¡£¡¡
4¡£¡¡Were¡¡there¡¡stylistic¡¡or¡¡content¡¡features¡¡of¡¡these¡¡proposals¡¡that¡¡made¡¡some¡¡more¡¡likely¡¡to¡¡be¡¡accepted¡¡
than¡¡others£»¡¡for¡¡example£»¡¡reference¡¡to¡¡prior¡¡research£»¡¡explicit¡¡mention¡¡of¡¡benefits¡¡of¡¡research£»¡¡basic¡¡
versus¡¡applied¡¡orientation£»¡¡rhetoric£»¡¡etc¡££¿¡¡
DISCUSSION£»¡¡EXTENSIONS£»¡¡AND¡¡EXPERIMENTAL¡¡VARIATIONS¡¡
1¡£¡¡Does¡¡the¡¡concern¡¡of¡¡an¡¡IRB¡¡unnecessarily¡¡limit¡¡scientific¡¡research£¿¡¡What¡¡are¡¡the¡¡drawbacks¡¡to¡¡such¡¡
a¡¡system¡¡of¡¡review£¿¡¡
2¡£¡¡What¡¡should¡¡the¡¡position¡¡be¡¡of¡¡an¡¡IRB¡¡at¡¡your¡¡school£»¡¡i¡£e¡££»¡¡what¡¡constituencies¡¡should¡¡be¡¡
represented£¿¡¡
3¡£¡¡How¡¡might¡¡the¡¡status¡¡of¡¡the¡¡researcher¡¡influence¡¡the¡¡IRB£»¡¡and¡¡how¡¡can¡¡this¡¡possible¡¡bias¡¡be¡¡
handled£¿¡¡
4¡£¡¡Can¡¡there¡¡ever¡¡be¡¡true¡¡informed¡¡consent¡¡for¡¡populations¡¡in¡¡coercive¡¡environments¡¡such¡¡as¡¡prisons¡¡
or¡¡for¡¡poor¡¡people¡¡who¡¡need¡¡the¡¡money¡¡they¡¡get¡¡for¡¡participating¡¡in¡¡the¡¡research£¿¡¡
5¡£¡¡How¡¡can¡¡research¡¡be¡¡conducted¡¡to¡¡demonstrate¡¡that¡¡deception¡¡has¡¡negative¡¡consequences¡¡if¡¡it¡¡is¡¡
judged¡¡unethical¡¡to¡¡deceive¡¡subjects£¿¡¡
6¡£¡¡What¡¡are¡¡the¡¡ethical¡¡issues¡¡in¡¡the¡¡treatment¡¡of¡¡animal¡¡subjects£¿¡¡£¨Perhaps¡¡obtain¡¡guidelines¡¡for¡¡such¡¡
research¡¡from¡¡your¡¡school¡££©¡¡
7¡£¡¡Make¡¡connections¡¡with¡¡previous¡¡sections£º¡¡
¡£¡¡How¡¡ethical¡¡was¡¡the¡¡section¡¡on¡¡guilt£»¡¡in¡¡which¡¡one¡¡volunteer¡¡was¡¡instructed¡¡to¡¡perform¡¡
actions¡¡outside¡¡the¡¡classroom¡¡so¡¡that¡¡he¡¡would¡¡¡°feel¡±¡¡like¡¡a¡¡criminal£¿¡¡
¡£¡¡Is¡¡suicide¡¡intervention¡¡ethical£¿¡¡Should¡¡people¡¡be¡¡allowed¡¡to¡¡freely¡¡make¡¡their¡¡own¡¡decision¡¡
428¡¡
in¡¡this¡¡matter£¿¡¡What¡¡are¡¡the¡¡limits¡¡and¡¡safeguards¡¡on¡¡what¡¡can¡¡be¡¡done¡¡under¡¡the¡¡name¡¡of¡¡
¡°education¡±¡¡or¡¡¡°therapy¡±¡¡that¡¡is¡¡not¡¡¡°research¡±£¿¡¡
¡£¡¡Relate¡¡this¡¡section¡¡to¡¡the¡¡one¡¡on¡¡impression¡¡management¡¡by¡¡analyzing¡¡how¡¡the¡¡
experimenters¡¡tried¡¡to¡¡manage¡¡favorable¡¡impressions¡£¡¡Have¡¡two¡¡stu